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KMID : 1007420180160030134
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Mood and Emotion
2018 Volume.16 No. 3 p.134 ~ p.139
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Korean Medication Algorithm for Bipolar Disorder 2018 : Safety and Tolerability
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Sohn In-Ki
Bahk Won-Myong
Yoon Bo-Hyun
Jon Duk-In
Seo Jeong-Seok
Kim Won
Lee Jung-Goo
Woo Young-Sup
Jeong Jong-Hyun
Kim Moon-Doo
Jung Young-Eun
Shim Se-Hoon
Song Hoo-Rim
Min Kyung-Jun
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Abstract
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Objectives : Treatment for bipolar disorder is often complicated by various clinical situations. We undertook a survey of expert opinions to facilitate clinical decisions in special situations such as weight gain, metabolic syndrome, hyperprolactinemia, genetic counseling, and treatment adherence.
Methods : A written survey that asked treatment strategies related to safety and tolerability, was prepared focused on weight gain, antipsychotic related hyperprolactinemia, lamotrigine related skin rash, treatment non-adherence and genetic counseling. Sixty-one expertsof the review committee completed the survey.
Results : In the case of weight gain related to medications, experts preferred exercise and education for diet-control. First chosen medications were lamotrigine, aripiprazole and ziprasidone. Recommendations based on expert survey results for treatment of bipolar patients in other special situations are outlined.
Conclusion : With limitation of expert opinions, authors hope that results of this study provide valuable information to make clinical decisions about treatment of bipolar disorder in complicated situations.
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KEYWORD
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Bipolar disorder, Weight gain, Non-adherence, Lamotrigine, Hyperprolactinemia, Genetic counselling, Algorithm
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